What is nandrolone, also known as 19-nortestosterone, is an endogenous androgen which exists in the male body at a ratio of 1:50 compared to testosterone.[citation needed] It is also an anabolic steroid (AAS) which is medically used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin). Nandrolone esters are used in the treatment of anemias, cachexia (muscle wasting syndrome), osteoporosis, breast cancer, and for other indications. They are not used by mouth and instead are given by injection into muscle or fat.
nandrolone side effects esters include symptoms of masculinization like acne, increased hair growth, and voice changes. They are synthetic androgens and anabolic steroids and hence are agonists of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). It has strong anabolic effects and weak androgenic effects, which give them a mild side effect profile and make them especially suitable for use in women and children. There are metabolites of Nandrolone that act as long-lasting prodrugs in the body, such as 5α-Dihydronandrolone.
Nandrolone esters were first described and introduced for medical use in the late 1950s. They are among the most widely used anabolic steroid worldwide. In addition to their medical use, They are used to improve physique and performance, and are said to be the most widely used anabolic steroid for such purposes.
Chemical Properties Crystalline Solid
Therapeutic Function Anabolic
Mechanism of action Nandrolone facilitates formation of body muscle mass and strengthens the process of osseous tissue development. The main indications for using It, as well as other anabolic steroids, are abnormal protein anabolism, asthenia, diseases accompanied by protein loss, adrenal insufficiency, steroid diabetes, and prolonged condition of sluggishness.
Safety Profile Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.nandrolone phenylpropionate vs deca
Synonyms: NADROLONE;17-beta-hydroxyoestr-4-en-3-one;17-HYDROXY-13-METHYL-2,6,7,8,9,10,11,12,14,15,16,17-DODECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE, 5-ANDROSTENEDIONE;17b-hydroxyestra-4-en-3-one;17BETA-HYDROXY-4-ESTREN-3-ONE;17BETA-HYDROXY-19-NORANDROST-4-EN-3-ONE;19-NORTESTOSTERONE;19-NORANDROSTENOLONE
CAS: 434-22-0
MF: C18H26O2
MW: 274.4
EINECS: 207-101-0
Product Categories: nandrolone series;API;Miscellaneous Biochemicals;Steroids;Steroid and Hormone;Inhibitors;Biochemistry;Hydroxyketosteroids;Intermediates & Fine Chemicals;Pharmaceuticals;434-22-0
Mol File: 434-22-0.mol
Nandrolone Chemical Properties
Melting point 120-125 °C
alpha D22 +55° (c = 0.93 in chloroform)
Boiling point 357.38°C (rough estimate)
density 1.0528 (rough estimate)
refractive index 1.4800 (estimate)
Fp 2℃
storage temp. Controlled Substance, -20°C Freezer
solubility Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka 15.06±0.40(Predicted)
color Dimorphic crystals from CH2Cl2/Et2O
Water Solubility 3.09g/L(25 ºC)
Merck 6365
BRN 2055849
InChIKey NPAGDVCDWIYMMC-IZPLOLCNSA-N
CAS DataBase Reference 434-22-0(CAS DataBase Reference)
NIST Chemistry Reference Nandrolone(434-22-0)
More Introduction：https://en.wikipedia.org/wiki/Nandrolone
