2-Amino-5-bromophenol is a chemical that is used as a substrate in the study of intracellular Ca2+ levels. It can also be used to study the activity of microperoxidases, enzymes that are involved in the metabolism of hydrogen peroxide and organic hydroperoxides. It has been shown to have anticancer activity against MCF7 cells, an estrogen receptor positive cell line. The anticancer activity may be due to the inhibition of protein synthesis by It binding to DNA. This binding prevents transcription and translation of genes that code for proteins involved in cancer cell proliferation and survival.
2-amino-5-bromopyridine is a white crystalline solid powder at room temperature and pressure.2-amino-5-bromopyridine belongs to pyridine derivatives, with remarkable basicity and common chemical properties of pyridine, it can be used as an intermediate in organic synthesis and medicinal chemistry, and it is mostly used in basic chemical research and the preparation of drug molecules. It has been reported in the literature that this substance can be used to synthesize biologically active molecules, protein kinase modulators, which can be used in the treatment of cancer.
2-AMINO-5-BROMOPHENOL powder Chemical Properties
Melting point 146-147 °C
Boiling point 265.0±25.0 °C(Predicted)
density 1.768±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form powder
pka 8.79±0.10(Predicted)
color brown
Safety Information
Risk Statements 43
Safety Statements 36/37
HS Code 2922290090
MSDS Information
Chemical Properties white to light yellow solid
More Introduction:https://pubchem.ncbi.nlm.nih.gov/compound/10130284