Nicotinamide adenine dinucleotide supplement For athletes, skeletal muscle growth, repair and energy availability are two of the most critical determinants of athletic performance, and NAD+ has a profound effect on both. Logically, therefore, supplementing with NAD+ or supplementing with raw materials and thereby increasing NAD+ synthesis is a sound nutritional strategy. In fact, as early as 1995, a study of NAD supplementation (in the form of NADH) in endurance athletes found that supplemented athletes had reduced oxygen consumption, increased respiratory quotient, reduced carbon dioxide exhalation, and reduced lactate levels during training, and that the reason for such significant changes may be due to the increased levels of ATP availability due to the supplementation of NAD-related supplements. Increased. These changes suggest that athletes may be able to oxidize carbohydrates more efficiently to fuel performance and sustain exercise for longer periods of time.
Nicotinamide adenine dinucleotide (NAD+)benefits
The benefits of NAD+Therapy directly related to mental health treatment include:
Restores cellular energy, metabolism and promotes cellular repair
Helps regulate cellular defense and reduces inflammation
Elevates mood and generates the feeling of calmness and happiness
Supports healthy aging and cognitive function
NAD infusion therapy is most effective when multiple infusions are conducted regularly over time. Long-term maintenance and cellular support contribute to less overall damage to your mitochondria, a slower aging rate, and better cognitive health.
General Description β-Nicotinamide adenine dinucleotide (NAD) is a ubiquitously found electron carrier and a cofactor. NAD+ contains an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.
Nicotinamide adenine dinucleotide (NAD+) dosage
Generally, NAD+ is administered by intravenous (IV) infusion, where a needle is used to inject NAD+ into a vein. Typical doses of NAD+ used in clinical studies range from 100 to 300 milligrams (mg) per day, given as one or more infusions over several days.
Subcutaneous injection is an alternative method of NAD administration in which the substance is injected under the skin. A prescription is needed for subcutaneous NAD+ injections. The injection is self-administered and is similar to an insulin injection. The dose range varies but is usually between 20 mg and 100 mg of NAD+.
The frequency of NAD+ injections may vary depending on individual needs and treatment regimens. Some doctors recommend weekly injections initially, followed by maintenance injections every few weeks or months. It is important to consult with your healthcare provider to determine the dose and frequency that is best for your specific situation.
Nicotinamide adenine dinucleotide (NAD+) side effects In the studies conducted thus far, people taking between 1000mg-2000mg per day have reported zero long term side effects. However, during the active infusion, some people may feel temporary nausea or stomach discomfort.
β-Nicotinamide adenine dinucleotide Chemical Properties
Melting point 140-142 °C (decomp)
alpha D20 -31.5° (c = 1.2 in water)
storage temp. -20°C
solubility H2O: 50 mg/mL
form Powder
color White
PH ~3.0 (50mg/mL in water)
Odor Odorless
Water Solubility Soluble in water at 50mg/ml
Merck 14,6344
BRN 3584133
Stability: Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKey BAWFJGJZGIEFAR-WWRWIPRPSA-N
EPA Substance Registry System Adenosine 5′-(trihydrogen diphosphate), P’.fwdarw.5′-ester with 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, inner salt (53-84-9)
More Introduction:https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide
