MOTS-C (Mitochondrial-derived Peptide MOTS-C) is a small peptide encoded by mitochondrial genes with multiple biologically active functions.
Biological functions
Regulating metabolism: It plays a key role in energy metabolism, can regulate insulin sensitivity, promote glucose uptake, reduce insulin resistance, and participate in the regulation of fatty acid oxidation, which helps to maintain the balance of intracellular lipid metabolism.
Cellular stress response: When cells are under stress, the expression level of It will change, which can activate the stress signaling pathway in the cell, enhance the cell’s stress resistance, reduce oxidative damage, and protect the integrity and function of the cell.
Aging and longevity related: It is closely related to the aging process and can delay cell aging by improving cell metabolism and stress response capabilities. In some model organism experiments, increasing the level of MOTS-C can prolong the lifespan of the organism.
Anti-inflammatory and antioxidant properties: It exhibits powerful anti-inflammatory and antioxidant properties, which can inhibit the production of inflammatory mediators, reduce oxidative stress, and provide a new strategy for the prevention and treatment of chronic diseases such as cardiovascular disease and diabetes.
MOTS-c benefits
Research done on this peptide has shown beneficial effects in reducing diabetes and obesity while also enhancing performance and longevity. Why does this happen? It assists proper mitochondrial function, and the mitochondria are the energy center of every cell in the human body. Research has shown that It is an exercise-mimetic peptide, meaning it makes the body think it is exercising even when it is not.
These are the benefits of It:
Regulates mitochondrial energy
Promotes the metabolism of fatty acid in the liver
Promotes metabolic homeostasis
Improves glucose regulation
Aids in the resistance of metabolic stress
Protects against insulin resistance
Promotes weight loss
Improves physical performance
Mots-c Side Effects
It is one of those peptides that rarely cause any major side effects.
The peptide is believed to be very safe for human consumption; however, limited research trials have been performed so far involving human subjects.
Therefore, you may need to be pretty careful before deciding to use It.
Nevertheless, It can cause redness and rashes at the administration site, so a little icing after a Mots-c injection can be helpful.
MOTS-c usage and dosage
It is now becoming a standard regimen to stack Mots-c with IGF1-LR3 and PEG MGF and use it as a monotherapy.
IGF1-LR3 increases fatty acid oxidation and enhances muscle repair by inhibiting myostatin. Additionally, you can supplement with PEG-MGF due to similar effects.
For this monotherapy to be effective, it is fundamental to increase 25-75 mcg per day for six weeks; for M-c, use 10 mg thrice a week for six weeks.
If you want to include PEG MGF in the stack, 200-300 mcg 2-3 times per week should be enough!
MOTS-c +CJC 1295/Ipamorelin
– Increased growth hormone production – Fat burning – Protein production – Stabilized insulin function
– MOTS-C: 10 mg thrice a week for 6 weeks – CJC 1295 and Ipamorelin dosages as per recommended guidelines
storage +4°C
Chemical Properties
density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
color Solid lyophilized powder
InChIKey WYTHCOXVWRKRAH-JIJBDQHHNA-N
More Introduction:https://en.wikipedia.org/wiki/MOTS-c
