what is Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.GHK-Cu peptide for sale.
Overview
Several copper(II)-peptide complexes occur naturally. In human plasma, the level of It is about 200 ng/ml at age 20. By the age of 60, the level drops to 80 ng/ml. In humans, GHK-Cu is proposed to promote wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth. Recent studies revealed its ability to modulate expression of a large number of human genes. And generally reversing gene expression to a healthier state. Synthetic It is used in cosmetics as a reparative and anti-aging ingredient.
Description Copper tripeptide, also known as [N2-(N-Glycyl-L-histidyl)-L-lysinato(2-)]copper or GHK-Cu, is a naturally occurring tripeptide. It was first isolated from human plasma but can be found in saliva and urine. During wound healing, it may be freed from existing extracellular proteins via proteolysis. Studies have shown that GHK-Cu has a maximal biological effect at 10-9 mol/L. And Its concentration in the body decreases with age.
Uses Copper tripeptide
(GHK-Cu) can be used as a skin antiaging agent. It could lead to the extracellular matrix accumulation increases in the rat wound model. Copper Peptide preparations were able to promote wound healing rates in diabetic ulcers and patients undergoing Mohs surgery. It could induce angiogenesis in rabbit models at 10?12 mol/L by acting as a chemoattractant for capillary cells. and may also improve the autocrine growth factor milieu in keloid fibroblasts. Also be doped into It can also be doped into binary binary PBDB-T: ITIC to tune the crystallinity and phase separation of the active layer, improving the performance of polymer solar cells.
Mechanism of action At this concentration (10-9 mol/L), GHK-Cu has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. It has been demonstrated that GHK-Cu stimulates cultured normal fibroblasts to synthesize collagen and induces a dose-dependent increase in the synthesis of glycosaminoglycans. It could stimulate the regeneration of skin, nervous tissue, bones, lungs, and liver, protect the liver from oxidative damage, restore the activity of irradiated fibroblasts, reduce inflammation, and increase levels of antioxidant enzymes.ghk-cu dosage
