Description Methyltrienolone bodybuilding, also called metribolone, is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug or a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and prostatic tumors.
Chemical Properties Pale Yellow Solid
Uses Methyltrienolone is a synthetic derivative of testosterone that is used in the medical field as an androgen and anabolic agent. It has been used to treat breast cancer, prostate cancer, and other cancers that are sensitive to hormones.
Biochem/physiol Actions Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. R1881, also known as methyltrienolone cycle, is a synthetic androgen. It is the gold standard AR agonist.
Methyltrienolone powder Chemical Properties
Melting point 170°
alpha D20 -58.7° (c = 0.5 in ethanol)
Boiling point 485.9±45.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥10mg/mL
form powder
pka 14.79±0.40(Predicted)
color light yellow to yellow
optical activity [α]/D -48 to -68°
InChI InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/s3
InChIKey CCCIJQPRIXGQOE-XWSJACJDSA-N
SMILES [C@@]12([H])CC[C@@](O)(C)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,7,21,r|
CAS DataBase Reference 965-93-5(CAS DataBase Reference)
More Introduction：https://en.wikipedia.org/wiki/Metribolone
