Yohimbine bodybuilding,It is a plant extract usually derived from the bark of the yohimbine tree. It is extremely stimulating and many people experience discomfort when taking it and should start with a low dose and gradually increase to the recommended dose. It may feel uncomfortable, and when this occurs the dosage needs to be lowered, and it is not recommended for sensitive people.
Yohimbine fat loss Principle
The beta subunit of the adrenergic receptor promotes fat loss by increasing levels of adenylate cyclase and cAMP (cyclic adenosine monophosphate). Whereas the corresponding alpha subunit inhibits lipolysis, the alpha subunit (especially alpha-2) decreases adenylate cyclase activity and cAMP levels.
Yohimbine, on the other hand, is a selective alpha-2 adrenergic receptor antagonist, which inhibits the alpha subunits and maintains adenylate cyclase activity and effects mediated through beta receptors, thus aiding in fat loss. In addition to this, It itself can reduce fat by increasing adrenaline.
Yohimbine fat loss effects
Some studies have tested the response of yohimbine in athletes, with a decrease in body fat of about 2% in 21 days when combined with dietary control. Experiments on the general population have also shown that Yohimbine increases endogenous adrenaline, improves the rate of fat burning, and seems to be more effective during exercise. However, some studies have also found that It has no weight loss effects. As far as the current research is concerned, It is more effective for fat loss in the exercising population and in people in a fasted state.
Yohimbine powder Chemical Properties
Melting point 231-233 °C(lit.)
alpha D20 +50.9 to +62.2° (ethanol); D20 +108° (pyridine); 20546 +129° (c = 0.5 in pyridine)
Boiling point 487.66°C (rough estimate)
density 1.1640 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility THF; DMSO; Chloroform;
form Solid
pka 14.39±0.40(Predicted)
color Beige
InChIKey BLGXFZZNTVWLAY-SCYLSFHTSA-N
SMILES [C@@H]1(O)[C@H](C(OC)=O)[C@]2(C[C@@]3(N(C[C@@]2(CC1)[H])CCC1C2=C(NC3=1)C=CC=C2)[H])[H]
LogP 2.730
CAS DataBase Reference 146-48-5(CAS DataBase Reference)
NIST Chemistry Reference Yohimbin e(146-48-5)
More Introduction:https://en.wikipedia.org/wiki/Yohimbine
