Semax is a synthetic analogue of the adrenocorticotropic hormone, a hormone responsible for the production of cortisol which in turn regulates glucose and lipid metabolism and helps to maintain blood pressure. In the hippocampus, S rapidly elevates the levels of brain-derived neurotrophic factor (BDNF), a protein important in encouraging growth and differentiation of new neurons and synapses. BDNF is active in the hippocampus, cortex, and forebrain and is important for memory, coordination, concentration, and learning. Semax also works to activate the dopaminergic and serotonergic systems to help prime the brain for action and to induce a controlled state of mental stress.
Semax benefits Over continued use, guests have seen benefits such as:Reduces anxiety and depression;Improves mental clarity, memory, and focus
Biological Functions Semax altered the expression of genes that modulate the amount and mobility of immune cells. It also could enhanced the expression of genes that encode chemokines and immunoglobulins. It can increase attention and short-term memory, improve Non-proliferative Diabetic Neuropathy, and can help during recovery from Stroke/Hypoxia
Mechanism of action
Though the exact mechanism of action of Sem is unclear, there is evidence that it may act through melanocortin receptors. Sem is a neuroprotective peptide, which aims to slow disease progression and secondary injuries by halting/slowing the loss of neurons and is neurorestorative.
Uses semax peptide has been prescribed for anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal and even chronic diseases such as ALS, Parkinson’s Disease, and Alzheimer’s. Sem has been known to be used as an Adderall alternative.
Clinical Use Semax has undergone extensive study in Russia and is on the Russian List of Vital & Essential Drugs approved by the Russian Federation government on December 7, 2011. Medical uses for Sem include treatment of stroke, transient ischemic attack, memory and cognitive disorders, peptic ulcers, optic nerve disease, and to boost the immune system.
semax peptide storage Store at -20°C
Boiling point 1335.2±65.0 °C(Predicted)
density 1.391±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: >2mg/mL
form powder
pka 3.43±0.20(Predicted)
color white to tan
Water Solubility Soluble to 2 mg/ml in water
InChIKey AFEHBIGDWIGTEH-YNWVLKOQNA-N
SMILES N1(CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCSC)CC1N=CNC=1)CC1=CC=CC=C1 |&1:4,15,21,25,29,38,r|
More Introduction:https://en.wikipedia.org/wiki/Semax
