Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species. Selank is often prescribed for its anxiolytic properties, immune improvement, gastric protection, and with opioid and alcohol withdrawal/ dependence. It also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity.
Mechanism of action It is known that the classical benzodiazepines act via gamma-aminobutyric acid (GABA) type A receptors. They enhance the GABA effect by allosteric modulation, which increases the frequency of opening of channels for chlorine ions. The S action mechanism may be related to its ability to affect the performance of the GABAergic system.
Effects of Selank
Selank (also known as nootropic peptide, anti-anxiety peptide) has a variety of biological activities, mainly including anti-anxiety, anti-depression, immunomodulation and neuroprotection.
Anti-anxiety and anti-depression
Selank peptide exerts its anti-anxiety and anti-depression effects by regulating neurotransmitter systems, especially the GABAergic and 5-hydroxytryptamine (5-HT) systems. It can enhance the activity of GABA and reduce the excitability of neurons, thereby exerting anti-anxiety and sedative effects. In addition, Selank peptide can also regulate the level of 5-HT, improve emotional state, and relieve depressive symptoms.
Immunomodulation
Selank peptide has an immunomodulatory effect and can enhance the body’s immune function. It enhances immunity by promoting the phagocytic ability of leukocytes and improving the body’s disease resistance.
Neuroprotection
Selank peptide can promote the expression and release of nerve growth factor (NGF), which plays a key role in the growth, survival and differentiation of neurons. It can also regulate synaptic plasticity, promote the repair and regeneration of nerve cells, enhance the plasticity of the nervous system, and help improve cognitive function and learning and memory ability.
Selank Peptide Dosage
The appropriate Selank peptide dosage depends on factors such as the patient’s current health, weight, and tolerance. Standard daily doses are between 250 mcg to 3 mg and can be given subcutaneously or intranasally. It is best to begin with a lesser dose and increase it dependent on how your body reacts. Importantly, the use of Selank peptide should be under the guidance of a healthcare professional to ensure safety and efficacy.
More Introduction:https://en.wikipedia.org/wiki/Selank
