Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species. Selank is often prescribed for its anxiolytic properties, immune improvement, gastric protection, and with opioid and alcohol withdrawal/ dependence. It also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity.
Mechanism of action It is known that the classical benzodiazepines act via gamma-aminobutyric acid (GABA) type A receptors. They enhance the GABA effect by allosteric modulation, which increases the frequency of opening of channels for chlorine ions. The S action mechanism may be related to its ability to affect the performance of the GABAergic system.
Selank mechanism of action
Antianxiety effect is expressed through the GABA system in the brain. Also blocks the levels of anxiety-improving neurotransmitters (norepinephrine) in the emotional centers of the brain, increases the levels of endogenous antidepressants, here enkephalins (similar to endorphins) – those substances already produced in our body.
Accelerates the production of mRNA in the hippocampus. mRNA – program, plan for the synthesis of protein structures in the hippocampus. Hippocampus – brain region, responsible for memory and learning.
Improves memory.
In high emotional stress, the effect is even greater than that of Piracetam. This is not surprising, because we usually show wisdom when we are not passionate emotions, but only calm reason.
Increases the level of serotonin, which decreases. Serotonin – a hormone of life pleasure, its low value is often associated with depression, Selank increases serotonin reduction.
After 24 hours, BDNF increases by 40%. BDNF – growth factor and protection of nerve cells, now recognized by modern medicine. So what nerve cells uniquely restore, although some still debate.
Reduces the side effects of benzodiazepines. Here, when strong poisons begin to disrupt the work of the body, Selank works as a good assistant to restore.
Effects of Selank
– Reduction of anxiety and stress – the main features of the drug. Reduced doubts and experiences.
– Improved mood charges of serotonin and enkephalin. As neurotrophic factor BDNF, in higher concentrations, thereby reducing depression.
– Increased efficiency due to increased synthesis of dopamine.
– Nootropic effect. This can also include growth in mRNA and hippocampus, simply put: faster synthesis of protein molecules located in the part of brain neurons responsible for memory and learning.
Selank Peptide Dosage
The appropriate Selank peptide dosage depends on factors such as the patient’s current health, weight, and tolerance. Standard daily doses are between 250 mcg to 3 mg and can be given subcutaneously or intranasally. It is best to begin with a lesser dose and increase it dependent on how your body reacts. Importantly, the use of Selank peptide should be under the guidance of a healthcare professional to ensure safety and efficacy.
More Introduction:https://en.wikipedia.org/wiki/Selank
