Dapoxetine Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) mainly used to treat premature ejaculation (PE) in men. The chemical name of dapoxetine hydrochloride is (S)-N,N-dimethyl-3-(naphthyl-1-oxy)-phenylpropylamine hydrochloride.
The indications of Dapoxetine Hydrochloride mainly include the treatment of male patients with premature ejaculation aged 18 to 64 years. Indications include: persistent or repeated ejaculation due to minimal sexual stimulation before, during or shortly after vaginal insertion; significant personal distress or interpersonal communication disorders caused by premature ejaculation; poor ejaculation control ability, etc.
Dapoxetine Hydrochloride Dosage
The dosage of It is oral. The tablets should be swallowed whole. It is recommended to take it with a full glass of water. The recommended first dose for adult males is 30 mg, which needs to be taken about 1 to 3 hours before sexual intercourse. If the effect after taking 30 mg is not satisfactory and no moderate or severe adverse reactions occur, the dosage can be increased to the maximum recommended dose of 60 mg. This product is not suitable for daily use and should only be taken when sexual intercourse is expected. The recommended maximum frequency of use is once every 24 hours.
Dapoxetine Hydrochloride Side Effects
It has shown certain safety and efficacy in clinical trials, but there have also been reports of some adverse reactions. Common adverse reactions include dizziness, nausea, diarrhea, etc. For different populations, such as the elderly, patients with renal impairment, and patients with liver impairment, special attention and dosage adjustments are required when using dapoxetine hydrochloride
Dapoxetine hydrochloride 30mg Chemical Properties
Melting point 175-1790C
alpha D +135.78° (c = 2.18 in methanol)
storage temp. room temp
solubility DMSO: ≥20mg/mL
form powder
color white
optical activity [α]/D +125 to +135°, c = 1 in methanol
Merck 14,2821
InChI InChI=1/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/s3
InChIKey IHWDIQRWYNMKFM-OZYVVJTJNA-N
SMILES O(C1=CC=CC2C=CC=CC1=2)CC[C@@H](C1C=CC=CC=1)N(C)C.Cl |&1:13,r|
CAS DataBase Reference 129938-20-1(CAS DataBase Reference)
More Introduction:https://en.wikipedia.org/wiki/Dapoxetine
