(2R)-3-Bromo-2-hydroxy-2-methylpropanoic acid is an organic compound with the chemical formula C4H7BrO3. It is a molecule with chirality and exists in two stereoisomers, with the dominant conformation of the (2R)-isomer.
Regarding properties,(2R)-acid is a solid and soluble in water. It is acidic and can react with bases to form the corresponding salts. In addition, it also has the ability of nucleophilic substitution reaction.
This compound has certain applications in the chemical and pharmaceutical fields. It can be used as an important intermediate in organic synthesis, and a variety of organic compounds can be prepared by other chemical reactions. Its acidity also makes it useful as a catalyst or catalyst precursor.
The preparation of (2R)-acrylic can be achieved by reacting 2-methyl-3-hydroxypropionic acid with bromine. By adding bromine to the solution under appropriate conditions, the reaction will be substituted and isolated and purified after formation of the brominated product.
Uses (2R)-3-Bromo-2-hydroxy-2-methylpropionic Acid powder is used as a reagent in the synthesis of [18F]-radiolabeled hydroxyflutamide derivatives as prostate cancer PET imaging agents.
(2R)-acid Chemical Properties
Melting point 113.0 to 117.0 °C
Boiling point 294.5±25.0 °C(Predicted)
density 1.831±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Methanol
form Solid
pka 3.39±0.16(Predicted)
color Off-White
More Introduction:https://pubchem.ncbi.nlm.nih.gov/compound/2R_-3-Bromo-2-hydroxy-2-methylpropanoic-acid
