A case study of the side effects of oral semaglutide

This is a summary of the side effects of taking semaglutide: It should be noted that this side effect is the only one that is very serious among the thousands of people who take semaglutide. Other customers either have no feedback or the side effects are very small and acceptable. The purpose of sharing this serious side effect is that if you use semaglutide, don’t panic if you have various side effects. You need to understand this serious side effect, but there is no need to be afraid:

My initial dose started with 3mg. After taking it, there were no side effects, but the feeling of hunger disappeared very obviously. On this basis, I gradually increased the dose to two 3mg tablets. After that, the physical feeling was fine, and the feeling of hunger continued to disappear significantly. There was no particularly obvious fluctuation in weight.

Then, a special situation came. I needed to go on a business trip, and I drank more frequently during the business trip. In total: I drank white wine twice, red wine once, and beer once. White wine was about half a catty each time, red wine was about a bottle, and beer was a pack. The next day after drinking these drinks, I was having lunch with a customer, and suddenly my stomach started to hurt. The pain came very suddenly, and the whole person was listless. It lasted for about 40 minutes, and then the pain disappeared. I returned to Beijing that afternoon, and everything was normal. The next day, I went to work and bought an iced sauce latte (because it was popular at the time). After drinking it, my stomach pain appeared again and lasted for about 30 minutes. I didn’t pay attention to it at the time. And drank another cup on the third day, and my stomach pain continued. I found that my stomach pain was directly related to drinking iced coffee, so I never drank it again. Unexpectedly, this was the beginning of a long period of side effects.

My symptoms appeared in several aspects: digestive system, taste, and psychology.
Digestive system

The stomach’s digestive ability weakened, and it was not digested even 8 hours after eating. There was even a situation where I vomited after lunch and went home after get off work in the evening. This situation caused bloating, and sometimes the bloating was severe. The bloating sometimes lasted for 2 hours. During these two hours, people basically couldn’t concentrate, and all their energy was fighting the discomfort.

Reflux. Because of bloating, belching occurred. While belching, you can feel that some of the food returned to the esophagus, forming a de facto reflux. This situation is very painful.

Vomiting. I vomited several times during this period, but I vomited at about 12 o’clock in the middle of the night after dinner, and then continued to rest. When I got up the next morning, I had hypoglycemia. I was weak all over and couldn’t support myself. I quickly ate two pieces of chocolate and slowly recovered.

Taste

The taste has changed. Many foods, especially carbohydrates, seem to have a strange smell. Not to mention the problem of appetite, sometimes I want to vomit while eating.

Psychology

During the whole period, people’s energy is difficult to concentrate, especially alienated, indifferent, and feel that everything is meaningless. I can’t do anything that requires concentration when I go home, and I’m too lazy to even follow the drama. I have never used Douyin, but I downloaded Douyin and watched it day and night.

My countermeasures during this period:

At first, I didn’t realize that it might be a side effect of the drug. While feeling uncomfortable, I continued to take it at a dose of 7mg. Initially, I thought there was something wrong with my stomach, so I bought PYLOPASS probiotics that can eliminate Helicobacter pylori and took it, but it didn’t work. After that, I felt really uncomfortable, so I bought the stomach medicine Daxi. It had a certain effect after taking it, but according to the instructions, if there are still symptoms after seven days, it is also ineffective. After that, I took Weixianyou, but the effect was not as good as I thought. Finally, I bought digestive enzymes imported from South Korea, which had a certain effect. However, the above health products and medicines all solved the problem of bloating and the resulting bloating and pain.

Later, I accidentally saw an article on the Internet that introduced the side effects of semaglutide. Especially the side effects on the digestive system, and even more serious symptoms such as gastroparesis. As a user who has been taking it for a while, I learned for the first time that it not only eliminates hunger, but also delays gastric emptying to achieve the purpose of eating less. I suddenly realized that I might be one of the few people with obvious side effects. I decided to stop taking the medicine immediately.

Progress after stopping the medicine

Today, it has been the fourth week since I stopped taking the medicine. If the half-life of the first week is included, today is the third week. According to what I learned online, the side effects of the digestive system caused by semaglutide will slowly disappear in about 5-8 weeks, so I still have two or three weeks of recovery time. During these three weeks, the frequency of bloating and pain has been significantly reduced, and it only occurred once in the past week. The frequency of vomiting has been greatly reduced. In the past two weeks, it has only occurred once. The stomach that once lost its feeling seems to be slowly returning. Everything is developing in a good direction.

The main problem at present is that the sense of taste has not been fully restored. Sometimes the food tastes a little strange. The appetite is average. Although I want to eat very much, I feel full after two bites. Secondly, there are individual cases of belching, but it will not cause reflux. Now I am particularly yearning for food. I watch food videos on Douyin. I want to eat everything I see. This can only be considered in the long run.

Summary

Semaglutide is a prescription drug, so you still have to be careful. If you really want to try it, start with 3mg.
The probability of having such serious side effects as mine is still very low (to be honest, I used to have a bad stomach), but you still need to pay attention. For example, if the drug delays gastric emptying, it is likely to cause belching, and belching causes food to return to the esophagus, which is likely to cause reflux. Or if the stomach cannot be emptied for 8 hours, it will definitely cause bloating and pain. This series of complex factors are difficult to grasp.
It is best not to drink alcohol after taking semaglutide. I can’t say that my condition was caused by drinking, but at least I was fine before I drank.
Even though I stopped taking the medicine, the effect was seen. I lost about 20 pounds.

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