Introduction to testosterone enanthate
Testosterone is a steroid hormone that is secreted by the testes in males or the ovaries in females, and to a lesser extent by the adrenal glands. Testosterone is the main androgen and anabolic steroid. It has important health effects in both men and women, including enhancing libido, strength, immune function, and combating osteoporosis.
Testosterone Enanthate is the earliest and most widely used anabolic steroid. It is a slow acting long chain testosterone. Testosterone was first extracted from a male bull in 1935, and over the years a number of different medicinal species have been developed. Synthetic testosterone was first available without an ester chain as a water-based suspension injection, which was fast acting but required frequent injections. 1937 saw the release of Schering’s Testosterone Propionate, which contained an ester that delayed the release of its effects, which allowed for less frequent injections. In the early fifties testosterone enanthate with a longer ester chain was introduced, which further slowed down the hormonal activity and testosterone enanthate became the ruler of the market, Testosterone Cypionate, which is not very different from testosterone enanthate, was also marketed a few years later.
Functions and Properties of Testosterone Enanthate:
Testosterone enanthate is a compound with a long chain ester on testosterone that is attached to the 17-beta hydroxyl group of the hormone. This mechanism controls the expiration and release time of the hormone. After injection, testosterone begins to be effective only after the ester chain is broken. This separation process is not done in one step, which allows the hormone to enter the body slowly and steadily, with a dramatic increase in testosterone 24-48 hours after injection, followed by a continuous diffusion throughout the body, during which time the half-life of testosterone enanthate is about eight days, and injections for therapeutic purposes can continue for up to once every two weeks, and once every seven to ten days to effectively increase its stability.
Like other testosterone hormones, testosterone enanthate has an anabolic and androgenic capacity index of 100.This index is based on testosterone, which, unlike other steroids, is structurally and functionally determined by its high anabolic and androgenic capacity.
Five properties of testosterone hormone:
1. Increased protein synthesis
Proteins are the raw materials that make up muscle tissue. Testosterone enanthate increases the rate at which the body synthesizes proteins, thus increasing anabolic activity and body recovery.
2. Increase nitrogen retention
Increasing nitrogen retention ensures an anabolic environment. The nitrogen content of muscle tissue is about 16%, below which catabolism occurs. Positive nitrogen balance means anabolism, which improves the ability to grow tissues and protects the muscle from loss.
3. Increased red blood cell count
An increase in red blood cells means an increase in muscular endurance. This is because red blood cells are responsible for transporting oxygen, and high blood oxygen equals high output, greater endurance and recovery.
4. Increased output
IGF-1 is a protein hormone (peptide) secreted mainly by the liver, with strong anabolic capacity for almost all cells. It is closely related to growth hormone, which acts on the healing and recovery of muscles, cartilage, nerves, tendons, ligaments and even the central nervous system.
5. Suppressing glucocorticoids
Glucocorticoids are steroid hormones secreted by the body, but their catabolic nature leads to muscle breakdown and fat accumulation. Cortisol is the most well known glucocorticoid, also known as the stress hormone, this hormone is necessary but not in large amounts, testosterone inhibits glucocorticoids the result is a more anabolic environment.
The role of testosterone enanthate:
Testosterone enanthate also has multiple benefits for athletes, the direction of its action depends on your diet and training, it is not just a muscle building or fat loss steroid, he can be used for a variety of purposes in the cycle.
Testosterone enanthate is an excellent choice for gaining lean body mass off-season, with adequate nutrition it can be used to rapidly gain size in a short period of time, of course you still need to eat and train well, testosterone can increase your metabolism rate which is good for fat burning but you still need to be careful not to consume too many calories.
The high levels of testosterone enanthate provided in the fat loss cycle also play an important role, during this phase the calorie deficit will threaten muscle tissue, your body will try to find ways to get energy, including protein for energy, a good diet plan should ensure that the maximum consumption of fat to retain muscle, when we become less fat, the body’s protective mechanism will automatically store fat to consume muscle, testosterone enanthate provide The high anabolism provided by testosterone enanthate at this point allows us to continue to burn only fat, and the dramatic increase in metabolic rate also allows for more effective fat burning.
Testosterone enanthate also dramatically increases muscle tolerance, you can train longer and harder with faster recovery, meaning more muscle stimulation in the gym and more anabolic recovery in the kitchen and bedroom, not only bodybuilders, but athletes in other disciplines can benefit from the tolerance and recovery that Testosterone enanthate provides, and one more thing, high levels of testosterone means strength gains, which is excellent for any athlete, and is especially good for bulking up in the off-season C. The role of the drug in maintaining strength levels is extremely important during periods of strict calorie control during a competitive bodybuilder’s season.
Testosterone enanthate side effects.
1. Estrogenization
The testosterone hormone in testosterone enanthate is converted to estrogen when it reacts with aromatase, elevated estrogen levels can lead to bitchy milk and excessive water retention, severe water retention can cause hypertension, which is basically not a problem for people with low testosterone, the danger increases with doses above physiological levels.
This calls for the use of anti-estrogenic drugs, of which there are two main classes: Selective Estrogen Receptor Modulators (SERM’s) or Aromatase Inhibitors (AI’s). Aromatase Inhibitors (AI’s). Tamoxifen Nolvadex (Tamoxifen Citrate) is a SERM, which binds to estrogen receptors and prevents estrogen from binding to them. Arimidex (Anastrozole) is an AI, which directly inhibits the aromatization process and lowers serum estrogen levels.AI is the preferred choice for testosterone enanthate anti-estrogens, but they can cause cholesterol problems, and are not dangerous on their own, but their side-effects are significantly enhanced when combined with testosterone external support.SERMs do not have this problem, so if a SERM can solve the problem, it is the preferred choice, but most of them can be used to prevent estrogen binding. can solve the problem it is the first choice, but most of the time testosterone is supraphysiologic level dose, AI is a must.
2. Androgenic effects
The androgenic side effects of testosterone enanthate can be severe but this depends on the genes, these side effects manifest as acne, hair loss (genetically predisposed to male pattern baldness) and increased body hair. People who don’t have a balding problem in their genes won’t lose their hair, and people who are not sensitive to acne acne rarely have problems.
The androgenic side effects of testosterone enanthate are due to testosterone’s ability to reduce dihydrotestosterone (DHT), a hormone metabolized by the enzyme 5-alpha reductase enzyme reductase, and Finasteride Finasteride, an inhibitor that targets this reductase enzyme, has a role in mitigating androgenesis, but not completely.
3. Cardiovascular effects
Exogenous testosterone suppresses and reduces HDL cholesterol (good cholesterol) HDL cholesterol (good cholesterol). This side effect of low dose testosterone enanthate is minimal, but if paired with 200-300 mg weekly AI can bring down HDL by 20-25%. Higher doses of 300-600 mg per week of testosterone enanthate alone reduce HDL by 13-21%, and when combined with an AI, this value rises significantly. This requires that people using testosterone enanthate pay attention to their cholesterol status on a regular basis, that their diets should be rich in omega fatty acids, that daily fish oil supplements are recommended, that they eat less saturated fats and simple carbohydrates, and that they do adequate aerobic exercise.
